Tarja Joensuu Selected Research

Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy)

1/2021	Progressive myoclonus epilepsies-Residual unsolved cases have marked genetic heterogeneity including dolichol-dependent protein glycosylation pathway genes.
4/2015	Refining the phenotype of Unverricht-Lundborg disease (EPM1): a population-wide Finnish study.
3/2015	Abnormal microglial activation in the Cstb(-/-) mouse, a model for progressive myoclonus epilepsy, EPM1.
1/2014	Gene expression alterations in the cerebellum and granule neurons of Cstb(-/-) mouse are associated with early synaptic changes and inflammation.
1/2012	Early microglial activation precedes neuronal loss in the brain of the Cstb-/- mouse model of progressive myoclonus epilepsy, EPM1.
5/2009	Cystatin B deficiency sensitizes neurons to oxidative stress in progressive myoclonus epilepsy, EPM1.
2/2007	Cystatin B: mutation detection, alternative splicing and expression in progressive myclonus epilepsy of Unverricht-Lundborg type (EPM1) patients.

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Tarja Joensuu Research Topics

Disease

7	Progressive Myoclonic Epilepsies (Progressive Myoclonic Epilepsy) 01/2021 - 02/2007
4	Neurodegenerative Diseases (Neurodegenerative Disease) 03/2015 - 02/2007
3	Seizures (Absence Seizure) 01/2018 - 01/2014
2	Unverricht-Lundborg Syndrome (Disease, Unverricht) 04/2015 - 05/2009
2	Ataxia (Dyssynergia) 03/2015 - 01/2014
2	Myoclonus (Nocturnal Myoclonus) 03/2015 - 01/2014
1	Brain Diseases (Brain Disorder) 01/2021
1	Muscle Hypotonia (Hypotonia) 01/2018
1	Benign Neonatal Epilepsy (Benign Familial Neonatal Convulsions) 01/2018
1	Megalencephaly 01/2018
1	PEHO syndrome 01/2017
1	Usher Syndromes (Usher Syndrome) 02/2007
1	Epilepsy (Aura) 02/2007

Drug/Important Bio-Agent (IBA)

7	Cystatin BIBA 01/2021 - 02/2007
2	Cysteine Proteases (Cysteine Protease)IBA 01/2021 - 01/2012
2	CathepsinsIBA 01/2021 - 02/2007
1	DolicholsIBA 01/2021
1	Pharmaceutical PreparationsIBA 01/2018
1	Codon (Codons)IBA 01/2017
1	Leucine (L-Leucine)FDA Link 01/2017
1	Proteins (Proteins, Gene)FDA Link 01/2017
1	Serine (L-Serine)FDA Link 01/2017
1	Mutant Proteins (Protein, Mutant)IBA 01/2017
1	OligonucleotidesIBA 02/2007
1	DNA (Deoxyribonucleic Acid)IBA 02/2007